I have a couple suggestions to help make it easier to connect with friends:
1) Right now I have a bit of trouble remembering who is who on my friends list. Sometimes I friend people I meet in-game, and some of my friends are old RL buddies from Facebook. The problem with the second group is that I might not recognize their Glitch username, but would very much like to interact with them. Would it be possible to pull in some Facebook info into profile pages of people who you are friended to on Facebook? An email or real name? It would make it much easier to track who all these "friends" actually are, which would in turn lead me to more in-game chat and collaboration.
2) It would be fantastic if there was something visual in the game UI that indicates that someone is your friend - maybe a halo or an aura or something. I've run right past avatars I know several times because I'm rushing to do something and don't really notice them. This is especially true when my friends like to change their clothes a lot; there's nothing to clue me in that it's someone I know.