I think it would be more convenient and less annoying for players if interactive items that have had all their interactions exhausted could be excluded from the pop-up menus that you get if you hit 'enter' near them.
For example, lets say I'm next to a piggy and a tree. I hit 'enter': the menu pops up with the tree and the piggy and I choose the tree. Then I pet the tree, then water it, then harvest it twice. I've done all I can to the tree. Let's say that the piggy is still hanging around close enough to show up in a pop-up menu. The next time I hit 'enter', Glitch should ignore the tree and bring up the piggy menu instead. If I see the tree again in the pop-up, that's just annoying and wastes a little bit of time for no good reason. If there were three or more interactive things nearby, then the tree should be excluded from the menu, but the other two or more should still be in there, obviously.
I think this would make things a bit more convenient, without taking away from the challenge of the game.