Running OSX 10.4.11, Safari 4.1.3, and Flash 10,1,102,64.
I can't get more recent versions of Safari or Flash since, as I understand, more recent versions only run on Intel Macs and I have a PowerPC Mac.
The actual situation:
Every time I try to "enter the world" all the windows pop up and I see the words "And so it begins". A bar at the bottom that's labeled "readying" fills up but once it's completed the browser freezes up for a few minutes. After a few minutes my avatar pops up amidst a bunch of neurons but I'm told that my session has "timed out" and the whole process starts over again. So far I have yet to play the game.